Ivermectin 6mg

Ivermectin 6mg is a potent antiparasitic medication widely used to treat various parasitic infections in humans. Initially introduced for veterinary use, it has since been adapted for human medicine due to its high efficacy and safety profile. Ivermectin acts against a range of internal and external parasites, making it a crucial drug in both tropical medicine and dermatology.

Composition:

Each Ivermectin tablet contains:

• Active Ingredient: Ivermectin – 6mg

Excipients:
May include lactose, magnesium stearate, microcrystalline cellulose, and other inert pharmaceutical ingredients depending on the manufacturer.

Mechanism of Action:

Ivermectin works by binding to specific chloride channels in the nerve and muscle cells of parasites, primarily glutamate-gated chloride ion channels. This binding increases the permeability of the cell membrane to chloride ions, resulting in hyperpolarization of the nerve or muscle cell, leading to paralysis and death of the parasite.

Importantly, Ivermectin has a higher affinity for parasite receptors than for those in humans, contributing to its safety profile.

Indications / Uses:

Ivermectin 6mg is prescribed for the treatment of the following parasitic conditions:

1. Intestinal Strongyloidiasis – Infection caused by Strongyloides stercoralis.

2. Onchocerciasis (River Blindness) – Caused by Onchocerca volvulus.

3. Scabies – Infestation by Sarcoptes scabiei mites.

4. Lice (Pediculosis) – Head lice and body lice.

5. Filariasis – As part of mass drug administration in endemic areas.

6. Cutaneous Larva Migrans – Skin infection caused by hookworm larvae.

7. Other Off-Label Uses – Rosacea (due to Demodex mites), COVID-19 (investigational use, not standard or approved).

Dosage & Administration:

• Adults and children ≥15 kg: Usually 150–200 mcg/kg as a single dose or as prescribed.

• Dosage may vary based on the infection being treated.

• It is generally taken on an empty stomach with water.

• A second dose may be required depending on the parasitic life cycle and response to treatment.

Example Dosage for Adults:

Side Effects:

Most side effects are mild and resolve on their own. Common ones include:

• Headache

• Dizziness

• Nausea

• Diarrhea

• Fatigue

• Rash or itching (especially with onchocerciasis)

Rare but Serious Side Effects:

• Low blood pressure

• Visual disturbances

• Encephalopathy (in patients with high parasite burden)

• Liver enzyme elevation

Always report serious or persistent symptoms to a healthcare provider.

Contraindications:

• Known hypersensitivity to Ivermectin or its components.

• Children weighing less than 15 kg.

• Use with caution in pregnant or breastfeeding women (consult a doctor).

Precautions:

• Liver Impairment: Use with caution as metabolism occurs in the liver.

• Neurological Disorders: Patients with a history of seizures or neurological issues should consult a doctor before use.

• Co-infection with Loa Loa: May cause severe adverse effects in patients with heavy Loa loa infections.

Drug Interactions:

Ivermectin may interact with the following:

• Warfarin (may increase INR)

• Other antiparasitic or antifungal medications

• CYP3A4 inhibitors or inducers (affects ivermectin metabolism)

Consult your healthcare provider if you’re taking any other medications.

Pregnancy & Lactation:

• Pregnancy Category C: Use only if the potential benefit justifies the potential risk.

• Breastfeeding: Small amounts of ivermectin pass into breast milk. Use with caution and under medical advice.

Storage Instructions:

• Store at room temperature (15°C to 30°C).

• Keep in a cool, dry place away from sunlight and moisture.

• Keep out of reach of children.

Frequently Asked Questions (FAQs):

Q1: Can Ivermectin be used for COVID-19?
A: Ivermectin has been studied for COVID-19, but major health organizations like the WHO and FDA have not approved it for prevention or treatment due to insufficient evidence. Use only under clinical trial or professional supervision.

Q2: How long does Ivermectin take to work?
A: Ivermectin typically starts working within 1–2 days. Symptom improvement depends on the infection type and severity.

Q3: Can I take Ivermectin with food?
A: It is best taken on an empty stomach, as food may alter its absorption.

Q4: What happens if I miss a dose?
A: Since it is usually taken as a single dose or spaced widely, missing a dose is rare. If prescribed multiple doses, take the missed dose as soon as possible unless it’s near the time for the next dose.

Disclaimer:

This description is for informational purposes only and is not a substitute for medical advice. Always consult your doctor or pharmacist before starting any medication.