Rifaximin 550 mg

Detailed Description — Rifaximin 550 mg

Rifaximin 550 mg is an oral antibiotic belonging to the rifamycin class. Unlike systemic antibiotics, rifaximin works locally in the gastrointestinal tract, making it highly effective for intestinal infections while minimizing absorption into the bloodstream.

It is commonly prescribed for:

• Irritable bowel syndrome with diarrhea (IBS-D)

• Traveler’s diarrhea caused by E. coli

• Small intestinal bacterial overgrowth (SIBO)

• Prevention of hepatic encephalopathy in liver disease (off-label in some cases)

Rifaximin’s targeted action helps control diarrhea, bloating, and abdominal discomfort caused by bacterial overgrowth in the gut.

How Rifaximin Works

Rifaximin works by:

• Binding to bacterial RNA polymerase, inhibiting bacterial RNA synthesis

• Preventing bacterial growth and replication

• Acting locally in the gut, which reduces systemic side effects

• Helping restore intestinal flora balance

Its localized activity is particularly advantageous for chronic gastrointestinal conditions, as it targets harmful bacteria without widespread antibiotic exposure.

Uses of Rifaximin 550 mg

Rifaximin 550 mg is prescribed for:

• IBS-D: Reduces diarrhea, bloating, and abdominal pain

• Traveler’s diarrhea: Short-term treatment for E. coli infections

• SIBO: Helps reduce bacterial overgrowth in the small intestine

• Hepatic encephalopathy prevention: Reduces risk of recurrent episodes in patients with liver disease (off-label use)

It is preferred for conditions where localized gut action is needed without affecting systemic bacterial populations.

Dosage & Administration

• IBS-D: 550 mg three times daily for 14 days

• Traveler’s diarrhea: Typically 200 mg three times daily for 3 days (check local guidelines)

• Swallow tablets whole with water

• Can be taken with or without food

• Complete the full course as prescribed, even if symptoms improve early

Dosage may vary based on condition, patient age, and doctor’s recommendation.

Benefits of Rifaximin 550 mg

• Highly effective against intestinal bacteria

• Minimal systemic absorption reduces side effects

• Improves diarrhea, bloating, and abdominal discomfort

• Can be safely repeated for chronic conditions under supervision

• Convenient oral administration

Possible Side Effects

Common side effects:

• Nausea or mild vomiting

• Stomach pain or bloating

• Headache

• Fatigue

Serious side effects (rare):

• Severe allergic reactions (rash, swelling)

• Clostridium difficile infection (rare but serious)

• Liver enzyme abnormalities

Patients should monitor for persistent diarrhea, abdominal pain, or allergic reactions.

Precautions & Warnings

• Do not use if allergic to rifamycin derivatives

• Use caution in patients with liver disease

• Not effective for systemic infections

• Avoid self-medication for prolonged periods

• Inform your doctor about all medications and health conditions before use

Drug Interactions

• Minimal systemic absorption reduces drug interactions

• May interact with cyclosporine or drugs metabolized by CYP3A4

• Avoid combining with other rifamycin antibiotics unless prescribed

Storage Instructions

• Store below 25°C in a dry place

• Keep tablets in the original packaging

• Protect from moisture and light

• Keep out of reach of children

• Do not use after expiry date

External Reference

For detailed medical information about rifaximin, visit:
🔗 https://www.drugs.com/monograph/rifaximin.html

Frequently Asked Questions (FAQ)

1. What is Rifaximin 550 mg used for?
It treats IBS-D, traveler’s diarrhea, SIBO, and prevents hepatic encephalopathy in some patients.

2. How does it work?
It inhibits bacterial RNA synthesis in the gut, reducing harmful bacteria locally.

3. Can it treat systemic infections?
No. Rifaximin acts mainly in the intestines and has minimal absorption.

4. How quickly does it work?
Symptoms may improve within 1–3 days, but the full course should be completed.

5. Can it be taken with food?
Yes, it can be taken with or without meals.

6. Are repeated courses safe?
Yes, short-term repeated courses are safe for chronic conditions like IBS-D under medical supervision.

7. What should I do if side effects occur?
Mild side effects usually resolve on their own. Contact a doctor if severe allergic reactions, persistent diarrhea, or liver issues occur.