Prednisolone dispersible tablets 5 mg (Generic Deltasone)

Prednisolone Dispersible Tablets 5 mg (Generic Deltasone) – Product Description

Prednisolone Dispersible Tablets 5 mg, commonly marketed as Generic Deltasone, are a type of corticosteroid medication designed to manage a wide range of inflammatory, autoimmune, and allergic conditions. Prednisolone is a synthetic glucocorticoid that mimics the effects of natural hormones produced by the adrenal glands, helping to reduce inflammation, suppress immune system overactivity, and alleviate symptoms associated with various chronic and acute conditions. The dispersible tablet form is particularly convenient for patients who have difficulty swallowing conventional tablets, as it can be dissolved in water or other suitable liquids for easier administration.

Prednisolone Dispersible Tablets 5 mg are widely used in both adults and children under medical supervision, offering flexibility in dosing to meet specific therapeutic needs. These tablets are commonly prescribed for patients who require precise dose adjustment, maintenance therapy, or gradual tapering after higher-dose corticosteroid treatment. Their rapid onset of action and ease of use make them an effective option for managing both long-term and acute flare-ups of inflammatory conditions.

Mechanism of Action

Prednisolone works by binding to glucocorticoid receptors in various cells throughout the body. This binding regulates gene expression, suppresses the production of inflammatory mediators such as prostaglandins and leukotrienes, and inhibits immune system overactivity. By reducing inflammation, it alleviates symptoms such as swelling, redness, stiffness, and pain, while preventing tissue damage caused by excessive immune responses.

Additionally, Prednisolone stabilizes cell membranes, reduces capillary permeability, and decreases the activity of immune cells in affected tissues. These combined actions provide both localized and systemic anti-inflammatory effects, making it a versatile and powerful therapeutic agent for a broad spectrum of medical conditions.

Uses and Indications

Prednisolone Dispersible Tablets 5 mg are prescribed for a wide range of conditions, including:

• Autoimmune disorders, such as lupus, rheumatoid arthritis, and multiple sclerosis

• Allergic conditions, including severe asthma, hay fever, and drug-induced allergic reactions

• Respiratory conditions, such as COPD exacerbations and asthma flare-ups

• Skin disorders, including eczema, psoriasis, and severe dermatitis

• Inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis

• Certain hematologic disorders and cancers, as part of combination therapy

The dispersible form of Prednisolone allows for easy administration, particularly in pediatric and geriatric patients who may have difficulty swallowing traditional tablets.

Dosage and Administration

Prednisolone Dispersible Tablets 5 mg should be taken exactly as prescribed by a healthcare professional. The tablet can be dissolved in water or a suitable liquid and ingested orally. The dosage depends on the patient’s condition, severity, age, and response to therapy. Gradual dose tapering may be necessary during long-term treatment to avoid withdrawal symptoms and adrenal insufficiency.

It is essential to follow the prescribed schedule carefully, as sudden discontinuation or irregular dosing can worsen symptoms or trigger flare-ups of the underlying condition.

Safety and Precautions

Prednisolone Dispersible Tablets 5 mg are generally safe when used as directed, but prolonged use may cause side effects. Common side effects include increased appetite, weight gain, mood changes, insomnia, and fluid retention. Long-term use can increase the risk of osteoporosis, elevated blood pressure, elevated blood sugar, and infections.

Patients with liver or kidney disorders, diabetes, hypertension, or a history of gastrointestinal ulcers should use Prednisolone under medical supervision. Pregnant and breastfeeding women should consult a doctor before using this medication. Regular monitoring and adherence to prescribed dosages are crucial to minimize risks and ensure treatment effectiveness.

Storage Guidelines

Store Prednisolone Dispersible Tablets 5 mg in a cool, dry place, away from direct sunlight and moisture. Keep the tablets in their original packaging and out of reach of children. Do not use the medication beyond the expiration date indicated on the label.

Additional Reference

For more information on Prednisolone and its clinical uses, refer to the Mayo Clinic guide:
https://www.mayoclinic.org/drugs-supplements/prednisolone-oral-route/description/drg-20075253